igf1 rabbit mab Search Results


pi3k akt agonist igf 1  (Sino Biological)
90
Sino Biological pi3k akt agonist igf 1
Knockdown of SHH induces cell-cycle arrest and apoptosis in WERI-Rb-1 cells. (A) Representative image and quantitative analysis of cell-cycle distribution. (B) Representative image and quantitative analysis result of apoptosis. (C) Representative images of Hoechst staining; nuclei of cells in shSHH group were stained bright blue and abnormally shaped (×400 magnification). (D) Representative image and quantitative analysis result of western blotting assay. a P<0.05 vs. control group; b P<0.05 vs. shNC group. SHH, sonic hedgehog; shSHH, short hairpin RNA targeting SHH; shNC, non-targeting short hairpin RNA; Bcl-2, B-cell chronic lymphocytic lymphoma 2; PARP, poly (ADP-ribose) polymerase; Bax, Bcl-2-associated X; <t>p-PI3K,</t> phosphorylated phosphoinositide-3 kinase; PI, phosphoinositide.
Pi3k Akt Agonist Igf 1, supplied by Sino Biological, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/pi3k akt agonist igf 1/product/Sino Biological
Average 90 stars, based on 1 article reviews
pi3k akt agonist igf 1 - by Bioz Stars, 2026-03
90/100 stars
  Buy from Supplier
igf1 rabbit mab  (Genecopoeia)
94
Genecopoeia igf1 rabbit mab
Knockdown of SHH induces cell-cycle arrest and apoptosis in WERI-Rb-1 cells. (A) Representative image and quantitative analysis of cell-cycle distribution. (B) Representative image and quantitative analysis result of apoptosis. (C) Representative images of Hoechst staining; nuclei of cells in shSHH group were stained bright blue and abnormally shaped (×400 magnification). (D) Representative image and quantitative analysis result of western blotting assay. a P<0.05 vs. control group; b P<0.05 vs. shNC group. SHH, sonic hedgehog; shSHH, short hairpin RNA targeting SHH; shNC, non-targeting short hairpin RNA; Bcl-2, B-cell chronic lymphocytic lymphoma 2; PARP, poly (ADP-ribose) polymerase; Bax, Bcl-2-associated X; <t>p-PI3K,</t> phosphorylated phosphoinositide-3 kinase; PI, phosphoinositide.
Igf1 Rabbit Mab, supplied by Genecopoeia, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/igf1 rabbit mab/product/Genecopoeia
Average 94 stars, based on 1 article reviews
igf1 rabbit mab - by Bioz Stars, 2026-03
94/100 stars
  Buy from Supplier

Image Search Results


Knockdown of SHH induces cell-cycle arrest and apoptosis in WERI-Rb-1 cells. (A) Representative image and quantitative analysis of cell-cycle distribution. (B) Representative image and quantitative analysis result of apoptosis. (C) Representative images of Hoechst staining; nuclei of cells in shSHH group were stained bright blue and abnormally shaped (×400 magnification). (D) Representative image and quantitative analysis result of western blotting assay. a P<0.05 vs. control group; b P<0.05 vs. shNC group. SHH, sonic hedgehog; shSHH, short hairpin RNA targeting SHH; shNC, non-targeting short hairpin RNA; Bcl-2, B-cell chronic lymphocytic lymphoma 2; PARP, poly (ADP-ribose) polymerase; Bax, Bcl-2-associated X; p-PI3K, phosphorylated phosphoinositide-3 kinase; PI, phosphoinositide.

Journal: Oncology Letters

Article Title: Blockade of sonic hedgehog signaling decreases viability and induces apoptosis in retinoblastoma cells: The key role of the PI3K/Akt pathway

doi: 10.3892/ol.2017.6701

Figure Lengend Snippet: Knockdown of SHH induces cell-cycle arrest and apoptosis in WERI-Rb-1 cells. (A) Representative image and quantitative analysis of cell-cycle distribution. (B) Representative image and quantitative analysis result of apoptosis. (C) Representative images of Hoechst staining; nuclei of cells in shSHH group were stained bright blue and abnormally shaped (×400 magnification). (D) Representative image and quantitative analysis result of western blotting assay. a P<0.05 vs. control group; b P<0.05 vs. shNC group. SHH, sonic hedgehog; shSHH, short hairpin RNA targeting SHH; shNC, non-targeting short hairpin RNA; Bcl-2, B-cell chronic lymphocytic lymphoma 2; PARP, poly (ADP-ribose) polymerase; Bax, Bcl-2-associated X; p-PI3K, phosphorylated phosphoinositide-3 kinase; PI, phosphoinositide.

Article Snippet: The PI3K/Akt agonist IGF-1 (cat. no. 10598-R023) was obtained from Sino Biological Inc. (Beijing, China).

Techniques: Staining, Western Blot, shRNA

Administration of PI3K/Akt agonist IGF-1 increases cell viability and inhibits apoptosis in WERI-Rb-1 cells. (A) Quantitative analyses results of MTT assay. (B) Representative image and quantitative analysis result of western blotting assay; the expression of anti-apoptosis molecules (Bcl-2, p-PI3K and p-Akt) was upregulated, while the expression of pro-apoptosis molecules (cleaved caspase 3, cleaved PARP and Bax) was inhibited. (C) Representative image and quantitative analysis result of apoptosis. a P<0.05 vs. shNC group; b P<0.05 vs. shSHH group; c P<0.05 vs. shNC+IGF-1 group. p-PI3K, phosphorylated phosphoinositide-3 kinase; IGF-1, insulin-like growth factor 1; MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; Bcl-2, B-cell chronic lymphocytic lymphoma 2; PARP, poly (ADP-ribose) polymerase; Bax, Bcl-2-associated X; shSHH, short hairpin RNA targeting SHH; shNC, non-targeting short hairpin RNA; OD, optical density.

Journal: Oncology Letters

Article Title: Blockade of sonic hedgehog signaling decreases viability and induces apoptosis in retinoblastoma cells: The key role of the PI3K/Akt pathway

doi: 10.3892/ol.2017.6701

Figure Lengend Snippet: Administration of PI3K/Akt agonist IGF-1 increases cell viability and inhibits apoptosis in WERI-Rb-1 cells. (A) Quantitative analyses results of MTT assay. (B) Representative image and quantitative analysis result of western blotting assay; the expression of anti-apoptosis molecules (Bcl-2, p-PI3K and p-Akt) was upregulated, while the expression of pro-apoptosis molecules (cleaved caspase 3, cleaved PARP and Bax) was inhibited. (C) Representative image and quantitative analysis result of apoptosis. a P<0.05 vs. shNC group; b P<0.05 vs. shSHH group; c P<0.05 vs. shNC+IGF-1 group. p-PI3K, phosphorylated phosphoinositide-3 kinase; IGF-1, insulin-like growth factor 1; MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; Bcl-2, B-cell chronic lymphocytic lymphoma 2; PARP, poly (ADP-ribose) polymerase; Bax, Bcl-2-associated X; shSHH, short hairpin RNA targeting SHH; shNC, non-targeting short hairpin RNA; OD, optical density.

Article Snippet: The PI3K/Akt agonist IGF-1 (cat. no. 10598-R023) was obtained from Sino Biological Inc. (Beijing, China).

Techniques: MTT Assay, Western Blot, Expressing, shRNA